Mechanosensitivity and Mechanotransduction

by Andre Kamkin

Publisher: Springer Science+Business Media B.V. in Dordrecht

Written in English
Published: Downloads: 497
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Subjects:

  • Biochemistry,
  • Life sciences,
  • Cytology,
  • Human physiology,
  • Cardiology

Edition Notes

Statementedited by Andre Kamkin, Irina Kiseleva
SeriesMechanosensitivity in Cells and Tissues -- 4
ContributionsKiseleva, Irina, SpringerLink (Online service)
The Physical Object
Format[electronic resource] /
ID Numbers
Open LibraryOL25551380M
ISBN 109789048198801, 9789048198818

Andre Kamkin, Irina Kiseleva, "Mechanosensitivity and Mechanotransduction" S-ger | | ISBN: | File type: PDF | pages | 10,2 mb This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Mechanosensitivity and mechanotransduction of the heart and vascular cells, in the lung, in bone and . The “Book of Hippocratic Treatment” by Al-Tabari, a 10th century Arab physician, may have provided some of the first references to intraocular pressure yet medieval Europe continued to categorize glaucoma as an incurable green (viriditas) cataract (“waterfall”) and “excessive hardness” of the lens (4). Integrin-mediated focal adhesions (FAs) are large multiprotein complexes, also known as the integrin adhesome, that link the extracellular matrix (ECM) to the actin cytoskeleton, and are part of powerful intracellular machinery orchestrating mechanotransduction by: 4. Mechanotransduction is an umbrella term to describe any biochemical cellular response generated against specific extracellular or intracellular mechanical stimuli [1,2,3,4,5].More precisely, mechanotransduction is the process that converts mechanical force into specific biochemical signals [6,7].The process involves force reception (mechanosensitivity/force recognition), force transduction Cited by: 9.

DEVELOPING INSTRUMENTATION FOR MULTI-PARAMETRIC INVESTIGATION OF MECHANISMS OF MECHANOSENSITIVITY IN ION CHANNELS Kalpesh V. Upadhye, PhD University of Pittsburgh, Mechanosensitive (MS) channels are implicated in pathologies of the renal and pulmonary : Kalpesh V. Upadhye. As a result, mechanosensitivity of the osteoblastic cells to the local mechanical stimulus depends on the angle of the applied deformation with respect to the cytoskeletal actin fiber orientation. This finding is phenomenological evidence that the cytoskeletal actin fiber structures are involved in the mechanotransduction mechanism in. Beyder A, Rae JL, Bernard C, Strege PR, Sachs F, Farrugia G. Mechanosensitivity of Nav, a voltage-sensitive sodium channel. J Physiol. ; (Pt 24). Kamaraju K, Gottlieb PA, Sachs F, Sukharev S. Effects of GsMTx4 on bacterial mechanosensitive channels in inside-out patches from giant spheroplasts. The majority of studies investigate intracellular signaling pathways. Currently, investigations of the molecular mechanisms of mechanosensitivity and mechanotransduction are focused on several issues. Integrin-mediated mechanotransduction, the role of actin cytoskeleton and the role of other cytoskeletal elements are discussed.

Textbook & Book Chapters 1. Raymond H. W. Lam and Weiqiang Chen, Biomedical Devices: Materials, Design, and Manufacturing, Springer Nature, ISBN 2. Lanqi Gong, Weiyi Qian, Jie Tong, Apratim Bajpai, Weiqiang Chen, Micro-Tweezers and Force Microscopy Techniques for Single Cell Mechanobiological Analysis, Handbook of Single Cell Technologies, edited by Tuhin Subhra . FMI is a dye which can be used to block mechanosensitive ion channels and therefore is a useful technique for studying mechanosensitive ion channels. For example, the blocking of certain subtypes results in a decrease in pain sensitivity, which suggest characteristics of that subtype with regard to mechanosensation.

Mechanosensitivity and Mechanotransduction by Andre Kamkin Download PDF EPUB FB2

For the first time mechanosensitivity and mechanotransduction in blood cells are discussed. It contains new insights into mechanosensitive K + channels functioning in mouse B lymphocytes. This book is a unique collection of reviews outlining current knowledge.

This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Mechanosensitivity and mechanotransduction of the heart and vascular cells, in the lung, in bone and joint tissues, in sensor systems and in blood cells are described in detail.

Mechanosensitivity and Mechanotransduction (Mechanosensitivity in Cells and Tissues) [Kiseleva, Irina, Kamkin, Andre] on *FREE* shipping on qualifying offers. Mechanosensitivity and Mechanotransduction (Mechanosensitivity in Cells and Tissues). ISBN: X: OCLC Number: Description: 1 online resource (xxiv, pages): illustrations.

Contents: Foreword by Holger Scholz; Editorial: Basic principles of mechanosensing and mechanotransduction in cells, Andre Kamkin and Irina Kiseleva; List of Contributors; Part I The Role of Cytoskeleton in Mechanosensitivity and Mechanotransduction: 1.

This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Mechanosensitivity and mechanotransduction of the heart and vascular cells, in the lung, in bone and joint tissues, in sensor systems and in blood cells are described in : Springer Netherlands.

Mechanosensitivity, i.e. the specific response to mechanical stimulation, is common to a wide variety of cells in many different organisms ranging from bacteria to mammals. Mechanical stress can modulate physiological processes at the molecular, cellular, and systemic level.

The primary target for mechanical stimulation is the plasma membrane of the cell, which can respond to Mechanosensitivity and Mechanotransduction book physical Cited by: This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues.

Mechanosensitivity and mechanotransduction of the heart and vascular cells, in the lung, in bone and joint tissues, in sensor systems and in blood cells are described in detail. This Volume focuses on molecular mechanisms of mechanosensitivity and.

Mechanosensitivity in Cells and Tissues. This book covers the following topics: Mechanosensitivity of Cells from Various Tissues, Molecular Mechanisms of Mechanotransduction, Mechanosensitivity of the Heart Cells: Fundamental Aspects and Clinical Implication, Mechanosensitivity of.

Mechanosensitivity, i.e. the specific response to mechanical stimulation, is common to a wide variety of cells in many different organisms ranging from bacteria to mammals.

Mechanical stress can modulate physiological processes at the molecular, cellular, and systemic level. The primary target for mechanical stimulation is the plasma membrane of the cell, which can respond to variable physical Cited by: 1.

Mechanotransduction. Mechanotransduction is a multistep process that includes (1) mechanocoupling (transduction of mechanical forces into signals sensed by sensor cells), (2) biochemical coupling (conversion of mechanical signal into a biochemical signal to elicit a cellular response such as gene activation), (3) transfer of a signal from sensor to effector cells, and (4) the effector cell.

Mechanotransduction is the process by which physical forces are sensed and converted into biochemical and electrical signals that then result in cellular responses. The discovery and elucidation of the various molecular pathways involved in this process have revolutionized the fundamental and clinical understanding of the formation and subsequent development of tissues and organs.

For the first time mechanosensitivity and mechanotransduction in blood cells are discussed. It contains new insights into mechanosensitive K+ channels in mouse B lymphocytes. This book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field.

Mechanosensitive channels, mechanosensitive ion channels or stretch-gated ion channels (not to be confused with mechanoreceptors).They are present in the membranes of organisms from the three domains of life: bacteria, archaea, and eukarya. They are the sensors for a number of systems including the senses of touch, hearing and balance, as well as participating in cardiovascular regulation and.

Specific Mechanotransduction Signaling Involved in Myogenic Responses of the Cerebral Arteries Koichi Nakayama, Kazuo Obara, Tomohisa Ishikawa, Shigeru Nishizawa Pages This book presents the latest findings in field of research of mechanosensitivity of the heart.

The Volume focuses on molecular mechanisms of mechanotransduction in cardiac cells. It contains a detailed description of several stretch-induced signaling cascades with multiple levels of crosstalk between different pathways.

Mechanotransduction by ENGLER, ADAM; KUMAR, SANJAY and a great selection of related books, art and collectibles available now at Mechanosensation is the transduction of mechanical stimuli into neural signals.

Mechanosensation provides the basis for the senses of light touch, hearing and balance, and pain. Mechanoreceptors found in the skin, called cutaneous mechanoreceptors, are responsible for the sense of touch. Tiny cells in the inner ear, called hair cells, are responsible for hearing and balance.

Mechanosensitivity of the Heart. Editors: Kamkin, Andre, Kiseleva, Irina (Eds.) Free Preview. This is the first series of books that considers the problem of cell mechanosensitivity of organs and tissues at the molecular, biological, bio-physical, physiological and pharmacological levels Book Title Mechanosensitivity of the Heart Editors.

In the review by Voglis and Tavernarakis [], presented in this book, they discuss models for mechanotransduction in C. elegans neurons, which implements. Mechanotransduction in Bone. Signal Transduction in Mechanosensing.

Single Cell Response to Mechanical Loading. Rate‐dependent Response by Bone Cells. Implications of Threshold Activation: Enhanced Response to Stochastic Stress. Stress Response and Cellular Deformation.

Towards a Quantitative Description of Bone Cell MechanosensitivityCited by: Feature: This is the first series of books that considers the problem of cell mechanosensitivity of organs and tissues at the molecular, biological, bio-physical, physiological and pharmacological levels and draws the attention to the global problem of the mechanosensitivity and its mechanisms.

André Kamkin is the author of Mechanosensitivity in Cells and Tissues, Volume 6 ( avg rating, 0 ratings, 0 reviews, published ), Mechanosensitivit. Biology in Space and Life on Earth: Effects of Spaceflight on Biological Systems.

Additional Information. How to Cite. Purchase Mechanotransduction, Volume - 1st Edition. Print Book & E-Book. ISBNMechanotransduction in bone: Genetic effects on mechanosensitivity in mice Article in Bone 31(5) December with 21 Reads How we measure 'reads'.

Living cells are constantly exposed to mechanical stimuli arising from the surrounding extracellular matrix (ECM) or from neighboring cells. The intracellular molecular processes through which such physical cues are transformed into a biological response are collectively dubbed as mechanotransduction and are of fundamental importance to help the cell timely adapt to the continuous dynamic Cited by: This paper addressed the possible mechanisms of primary reception of a mechanical stimulus by different cells.

Data concerning the stiffness of muscle and nonmuscle cells as measured by atomic force microscopy are provided. The changes in the mechanical properties of cells that occur under changed external mechanical tension are presented, and the initial stages of mechanical signal Cited by: Mechanosensitivity of the Heart By Wolfgang A.

Linke (auth.), Andre Kamkin, Irina Kiseleva (eds.) | Pages | ISBN: | PDF | 15 MB. Faculty page for Dr. Wissam AbouAlaiwi, University of Toledo College of Pharmacy and Pharmaceutical Sciences.

Visit. Apply. Book Chapter. Mechanosensitivity and Mechanotransduction. Mechanosensitivity in Cells and Tissues. () Volume 4, Part 6, Keywords: hair cell, mechanotransduction, deafness, lateral line, zebrafish, LHFPL5, TMC1, PCDH Citation: Erickson T, Pacentine IV, Venuto A, Clemens R and Nicolson T () The lhfpl5 Ohnologs lhfpl5a and lhfpl5b Are Required for Mechanotransduction in Distinct Populations of Sensory Hair Cells in Zebrafish.

Front. : Timothy Erickson, Timothy Erickson, Itallia V. Pacentine, Alexandra Venuto, Rachel Clemens, Teresa N.

Mechanosensitive Ion Channels by I. Lozinsky,available at Book Depository with free delivery worldwide.mechanical loading plays a major regulatory role that determines the size, shape, architectural integrity, and strength of the bone ().Although osteoblasts, stem cells, and other cells are capable of sensing and responding to mechanical stimuli (13, 15, 17, 57), there is increasing evidence that the osteocyte is the primary mechanosensory cell type in by: Purchase Mechanosensitive Ion Channels, Part B, Volume 59 - 1st Edition.

Print Book & E-Book. ISBN